The simplest connection to the Loxone control succeeds with the SMT100 analog 0 - 10 V. However, the disadvantage is that you need a separate analog input for each sensor. If you want to measure the temperature in addition to the humidity, you need 2 analog inputs. If there are several sensors, a bus system is more suitable. From Loxone there is a so called Modbus Extension, to which up to 32 sensors can be connected. For this you need the SMT100 RS-485 Modbus version.